CSB327H1 Lecture Notes - Lecture 5: Phosphate, Apoptosis, Coiled Coil
13 Jan 2018
School
Department
Course
Professor
Document Summary
Two major types of ecms: basal lamina (bl) or basement membranes: thin, sheet-like ecm upon which epithelial cells rest, surround muscle and adipose cells, peripheral nerves, connective tissue ecm: most abundant, e. g. Migration, secretion, communication, apoptosis, pattern formation, tissue remodeling, Csb327h1 tt1 notes made by man lai ho. Common features: one or more basic aa residues (+) followed by continuous. One gtp for srp and one gtp for each srp receptor (sr and sr = dimer) Only need 1 srp to recognize all signal peptides. D banding morphology, crimped with alternating dark and light transverse: hydrophobic signal peptide diffuse into bilayer, rapidly degraded by signal. Peptide peptidases: protein from er -> golgi apparatus -> secretory vesicles -> cell surface -> Fibroblast cells: cells of connective tissue that produce and secrete ecm molecules: occurs in various shapes (e. g. fusiform/spindle-shaped, stellate/star-like, morphologically heterogeneous.
