CSB328H1 Lecture Notes - Lecture 1: Petri Dish, Zebrafish, Xenopus
13 Sep 2016
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Document Summary
Likelihood of getting cancer increases (developmental disease: puberty. Muscle mass: morphological differences between males and females. Baby undergoes developmental changes every day: changes in body proportion, brain development. Young adults are in homeostasis: but there is continuous regeneration of cells for maintenance, stem cells. Similar to lizard or mouse embryo (and other vertebrates) The pharyngeal arches in this stage develop into: Parts of upper and lower jaw in reptiles and birds. Middle ear in human and other mammals. Human embryo has a long tail at this point and we develop an inner tail (tailbones) but not an outer tail: human head gets very large in comparison to the rest of the body. Life starts as a single cell (fertilized egg) We need animals to allow us to investigate developmental mechanisms: model organisms (ultimately applicable to human development) Follow cell divisions, cells movements, cell differentiation. Physical manipulations: cell ablation, tissue transplantation, injections.
