CSB346H1 Lecture Notes - Lecture 6: Intracellular Ph, Phrenic Nerve, Control Of Ventilation

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26 Mar 2013
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Csb346 lecture 6 central chemoreception (february 12, 2013) We want to move away from how the rhythm is generated. We want to think about how the rhythm is affected by stimuli that we know are critical. We are going to talk about central chemoreceptors. We talked about how the pre-b tc is responsible for generating the rhythm. The rhythm is sent to the respiratory mns (e. g. , hypoglossal and phrenic). Those muscles generate the force that enables muscle contraction so that ventilation can occur. Respiratory frequency multiplied by volume gives you ventilation. Co2 is the most powerful stimulus for breathing. You breathe to acquire oxygen, but you breathe because co2 makes you breathe. Breathing depends not only on the pre-b tc to generate it, but it also has to have input from other things that detect changes in o2 and co2 level.

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