CSB447H1 Lecture Notes - Lecture 2: Fowl Cholera, Louis Pasteur, Lactate Dehydrogenase
Document Summary
Lecture 2: recognized microbes responsible for alcoholic fermentation and many diseases. Pasteur discovered that microbes existed: germ theory vs spontaneous generation vs chemical theory, pasteurization milk, beer, wine, vinegar, fermentation - pasteur effect remove oxygen- result increased glucose utilization and begin ethanol production. Have to go anoxic, then you produce ethanol: vaccines for: cholera, anthrax, rabies, and solution to silkworm disease, understood that microbes responsible for human infection many men didn"t die from battle, but from wounds. Methods to sterilize: fight with animal activists. (victorian anti-vivisectionists) Economically very important: germ theory vs. spontaneous generation. Life gives rise to life vs. life appears or is created. System growth of organisms in beaker on windowsill. Boil beaker or flask of h2o and seal it: life does not appear, expose to microbes in air, life does appear! Studied lactic acid production in milk, ethanol in wine and beer, and acetic acid in vinegar.
