CSB332H1 Lecture Notes - Lecture 19: Operant Conditioning Chamber, Anterograde Amnesia, Cerebral Cortex
4 Apr 2013
School
Department
Course
Professor
Document Summary
Associative ltp: storage of new information -> establishing new synapses; Key components: need 2 stimuli, 2 axons or more; principle of cooperativity. Objective: in order to sufficiently depolarize the ps neuron -> open nmda receptors (dislodge mg) Ca influx through nmda receptors is important in maintaining conc of ca in ps neuron -> activate several types of biochemical pathway. > phosphorylation of transcription factors -> gene transcription -> increase in proteins needed to make more synapses -> information will linger for longer periods of time. Ltp also occurs in many other parts of the brain thus subserving many other types of learning and memory. Really not clear whether associative ltp is what causes ltm storage but it"s a hypothesis. So far, we"ve talked about ltp in hippocampus. Hippocampus - declarative, episodic, somatic memory are stored in ltm. Procedural or implicit types of memories are ones we"re not conscious about obtaining or learning.
