EEB202H1 Lecture : Integument Lecture

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The dermis develops from the mesoderm and mesenchyme and produce sthe reticular lamina: between the integument and the deep body musculature is a transitional subcutaneous region made up of loss connective and adipose tissues. In microscopic examination, this region is termed the hypodermis. Embryonic origin and development of skin: by the end of neurulation in the embryo, most skin precursors are delineated. The single-layered surface ectoderm proliferates to give rise to the multilayered epidermis: the deep layer of the epidermis, the strautum basale (strautum germinativum), rests upon the basement membrane. Through active cell division, the stratum germinativum replenishes the single layer of outer cells called the periderm: the dermis arises from several sources,principally from the dermatome. The segmental epimeres (somites) divide, producing the sclerotome medially, the embryonic source of the vertebrae, and the dermomyotome layerally. Inner cell of the dermomyotome become rearranged into the myotome, the major source of skeletal muscle.

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