HMB200H1 Lecture Notes - Lecture 3: Active Transport, Rna, Nernst Equation

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13 Sep 2018
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Hmb200: lecture 2; how does the brain communicate. The brain like a city: brain/city analogy is meant to describe the brain structures of connectivity drives the function. Thalamus; severs as integrating/relay center while amygdala is like a dispatcher. The thalamus-amygdala connections is almost as fast as spinal reflexes are. Every sensory organ has its own sensory neurons that detects stimulus. Sensory signals activate sensory receptors: within these neurons are specialized proteins called ion channels. The giant squid had giant axons that allowed us to discover relative conc. Found transient movement of ion produced a predictable waveform in axon eventually called action potential. There is more k+ in the cell then na+ Ca2+ has protein-activating properties rather than electrical signals. Measurement of conc: active transport of ions move them against conc. Gradient: na+/k+ pump - moves 3 na+ out and 2 k+ in, conc. To differentiate conc/ gradients result in diffusion if those molecules are allowed to flow.

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