HMB200H1 Lecture Notes - Order Of Newfoundland And Labrador, Parallel Fiber, Granule Cell
Document Summary
Lecture 24: classical conditioning: from reflex to consciousness. Events can change visceral relaxes and pavlov condition reflexes. Conditioned reflex: tone (cs) plus food (us) Laws of conditioning: cs- us pairing, extinction, recovery, generalization, etc. Pavlov speculated classical condition occurred in the cortex proposed humans learn in the cortex. Thought higher human functions were due to classical conditioning in the cortex. Search for engram: lesions of cortex don"t block learning of mazes or conditioning (lashley). Conditioning is not blocked when u remove the cortex (lashley) Correlates of learning: whole cortex active initially. Easy to measure in rodents and humans. Unconditioned reflex (us- shock and ur) in brain stem (two synapses). Tone (paired) with the shock, can then produce the eye blink response. After repeated trials, cs alone (with shock) can result in the eye blink response = conditioned response. Activity in hippocampus and cerebellum correlates with acquisition of delay conditioning. Hippocampus not critical; ipsilateral cerebellum is.
