HMB201H1 Lecture Notes - Lecture 5: Resting Potential, Axon Terminal, Printed Circuit Board

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14 Nov 2012
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Lecture 5-Nervous system II
Membrane potential, used to communicate
UPSH: pink, green or yellow. Some individuals called backyard brains. You see a bunch
of different colors and you have one common nerve and you attach it to an electrode,
every time a base note is hitting, you will see the chromoferes being released. Watch the
video\
Actual nervous system is like a circuit board, you can pass the electricity from an electron
server to a living organism.
This is all because of changes of membrane potential\
In a cell, you will have a resting membrane potential thatwill vary. Resting membrane
around -70. If there is in flux of more postivie ions and cells become more + on the inside
=depolarization, if its negative on the inside called repolarization
Your gonna have a lot more Na on the outside and K on the inside. WHY? The sodium
potassium pump is gonna be regulating the amouints which lead to a resting membrane
potential.
With regards your gonna have a more on the inside because you have + outside. 3
sodium OUT 2 potassium IN. The inside of the cell has a more charge.Neurons have a
resting membrane potential. Neurons are excitable. Excitable is a rapid change inMV.
DEPOL- interiorbecoming more positive; Na comes in. HYPERPOLARIZATIOn-
interioris becoming morenegative; k comes in.repolarization- your membrane returns to
its resting value. Changes in the membrane potentials act as electrical signals
Neurons receive from receptor, cgoes through the intergrating centre. Cell body +
dendrites receive the info. It gets integrated in the axon hilack. At the axon hilack is
where the cell determines if there is going to be an axon potential . IF YESH; it goes
through mylenated sheath [go fast] + signal comes out through the axon terminal. Since
it’s a muscle cell, its going to be a neurotransmitter
SIGNALS IN DENDRITES + CELL BODY
Receptors on the cell body + dendrites. WHAT HAPPENS? The receptor is gonna transducer the
info into the cell. USUALLY their voltage gated that will lead to changes in the ion. With the
receptor your transducing a chemical reaction. Electrical cell is the ion permeability. The change
in the ion permeabiklity causes a gradient condition. Within the dendrites + cell body, there is
always a gradient bodyl Its limitied by distance + size.
Stimulus strength + graded potential
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Document Summary

You see a bunch of different colors and you have one common nerve and you attach it to an electrode, every time a base note is hitting, you will see the chromoferes being released. Actual nervous system is like a circuit board, you can pass the electricity from an electron server to a living organism. This is all because of changes of membrane potential\ In a cell, you will have a resting membrane potential thatwill vary. If there is in flux of more postivie ions and cells become more + on the inside. =depolarization, if its negative on the inside called repolarization. Your gonna have a lot more na on the outside and k on the inside. The sodium potassium pump is gonna be regulating the amouints which lead to a resting membrane potential. With regards your gonna have a more on the inside because you have + outside.

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