HMB265H1 Lecture Notes - Lecture 13: Epistasis, Random Effects Model, Selective Breeding

• School: UTSG
• Department: Human Biology
• Course: HMB265H1
• Professor: Maria Papaconstantinou

Document Summary

Lecture 13 outline: quantitative trait analysis, heritability, broad-sense heritability, narrow-sense heritability, analyzing quantitative traits using two concepts of heritability, heritability is a statistical measure that helps us measure the genetic variance compared to environmental variance. Determining whether there are genetic effects buried within a quantitative trait. The more viable it is, the more distributed the trait will be in the population. Phenotypic variance is measured by taking the difference between each individual in the population, compared it to the mean of that population, and square it. To measure phenotypic variation of stem length of dandelions, we calculate the mean of the population, then look at the average of the squared difference: variance. To plot the magnitude of that variance on the bell-shaped distribution of individual stem lengths, the square root of the variance is shown so as to be in the same units as stem length (standard deviation)