Notes taken during lecture

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14 Jan 2011
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Sliding scale for any range of phenotypes โ€“ for instance dis eases
๎€Some diseases have strong, simple genetic basis, no major role for environment
๎€Heart disease and diabetes โ€“ genetic and environmental component
How does inheritance work?
๎€Important for Mendel to look at simple traits to understand inheritance
Agriculture โ€“ cattle and crops with favourable traits chosen to breed
These questions had no answers until Mendelโ€™s paper
๎€Except for how new characteristics appear
Rapid generation time โ€“ so can look at generations; maturation time from baby to adult in shor t span of
time
Look the same every generation โ€“ highly homozygous in these lines
Removal of anthers so plant doesnโ€™t self-fertilize
Also important that peas/models have discrete options for traits
^0^
Long v. short stems โ€“ discrete type of inheritance
Dominance โ€“ all of plants were one phenotype
In F1 generation, trait present is called dominant; missing trait is recessive
Hybrid generation is the f1 generation
Green and yellow in F2
Green, recessive, appeared in next generation โ€“ no mixing of the two colours, into an intermediate colour
that persisted into the next generations
Direction conclusions
๎€Both parents contribute hereditary material
Basic idea that adult plant that makes yellow seeds
Probability theory
๎€Mutually exclusive means both at the same time is impossible
๎€Or canโ€™t happen at the same time
๎€Very useful rules ************
๎€P(a) + P(b) = a or b
๎€P(a) times P(b) = a and b
๎€***Above two are all probabilities
Must use and rul e in 23 slide
Testing the model
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Document Summary

Sliding scale for any range of phenotypes for instance diseases. Some diseases have strong, simple genetic basis, no major role for environment. heart disease and diabetes genetic and environmental component. Important for mendel to look at simple traits to understand inheritance. Agriculture cattle and crops with favourable traits chosen to breed. These questions had no answers until mendel"s paper. Rapid generation time so can look at generations; maturation time from baby to adult in short span of time. Look the same every generation highly homozygous in these lines. Also important that peas/models have discrete options for traits. Long v. short stems discrete type of inheritance. Dominance all of plants were one phenotype. In f1 generation, trait present is called dominant; missing trait is recessive. Green, recessive, appeared in next generation no mixing of the two colours, into an intermediate colour that persisted into the next generations. Basic idea that adult plant that makes yellow seeds.

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