Notes taken during lecture

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Published on 14 Jan 2011
School
UTSG
Department
Human Biology
Course
HMB265H1
Sliding scale for any range of phenotypesfor instance dis eases
Some diseases have strong, simple genetic basis, no major role for environment
Heart disease and diabetes – genetic and environmental component
How does inheritance work?
Important for Mendel to look at simple traits to understand inheritance
Agriculturecattle and crops with favourable traits chosen to breed
These questions had no answers until Mendels paper
Except for how new characteristics appear
Rapid generation timeso can look at generations; maturation time from baby to adult in shor t span of
time
Look the same every generation – highly homozygous in these lines
Removal of anthers so plant doesnt self-fertilize
Also important that peas/models have discrete options for traits
^0^
Long v. short stems – discrete type of inheritance
Dominanceall of plants were one phenotype
In F1 generation, trait present is called dominant; missing trait is recessive
Hybrid generation is the f1 generation
Green and yellow in F2
Green, recessive, appeared in next generation – no mixing of the two colours, into an intermediate colour
that persisted into the next generations
Direction conclusions
Both parents contribute hereditary material
Basic idea that adult plant that makes yellow seeds
Probability theory
Mutually exclusive means both at the same time is impossible
Or cant happen at the same time
Very useful rules ************
P(a) + P(b) = a or b
P(a) times P(b) = a and b
***Above two are all probabilities
Must use and rul e in 23 slide
Testing the model
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Document Summary

Sliding scale for any range of phenotypes for instance diseases. Some diseases have strong, simple genetic basis, no major role for environment.  heart disease and diabetes genetic and environmental component. Important for mendel to look at simple traits to understand inheritance. Agriculture cattle and crops with favourable traits chosen to breed. These questions had no answers until mendel"s paper. Rapid generation time so can look at generations; maturation time from baby to adult in short span of time. Look the same every generation highly homozygous in these lines. Also important that peas/models have discrete options for traits. Long v. short stems discrete type of inheritance. Dominance all of plants were one phenotype. In f1 generation, trait present is called dominant; missing trait is recessive. Green, recessive, appeared in next generation no mixing of the two colours, into an intermediate colour that persisted into the next generations. Basic idea that adult plant that makes yellow seeds.