HMB265H1 Lecture : Notes taken during lecture

• School: UTSG
• Department: Human Biology
• Course: HMB265H1
• Professor: Stephen Wright

Document Summary

Resembling the male parent none will resemble the male parent phenotypically. Lecture 03: molecular basis of genetic polymorphisms and their detection. Mendel"s laws of segregation from pov of present knowledge. Mendel was looking at variation encoded at dna level ultimately effecting protein level, then affecting traits. allelic differences can impact any part of the pathway. Follow mendel"s laws but no dominant or recessive allele at dna because this is the genotypic level (one exception) point mutations single change in dna. allelic variation that may end up leading to phenotypic variation. gene ultimately leads into protein, which functions or confers a trait. amino acid replacement mutation change in protein folded different, functioning differently. mutation in promoter region that blocks rna transcription no protein effect on phenotype. Figure 2-15: all possible spots that could lead to novel allele.