HMB200H1 Lecture Notes - Lecture 3: Immunocytochemistry, Resting Potential, Tight Junction
Document Summary
Lecture 3: proteins and transmitters. Protein chains can be read from dna in genome. Hydrophilic and lipophilic regions: lipids bind to membranes. Trafficking in cell by tail code. Voltage- gated na+ channel (a protein) Needed for action potentials. One single chain interacting with the membranes. Many of these amino acids are lipophilic attracted to lipid membranes. These chains of amino acids then bind the membrane and form transmembrane loops. 24 transmembrane loops in voltage gated na+ channel. Many other amino acids attract to water (sits in the fluid part - cytosol) hydrophilic. Transmembrane protein is made of lipophilic and hydrophilic loops (chain folds up to interact in their respective favourable environment) 3d structure: capable of having a voltage gated property. Voltage- gated channels (how they fold up) Bars: lipophilic transmembrane part of protein lipophilic portions surrounds the pour where ions flow. These h bonds can be identified. If you want to know which genes are expressed, you look for.
