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Lecture 3

Lecture 3 - Proteins & Transmitters

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Human Biology
John Yeomans

HMB200H1S L3 Jan 17 2012Proteins and TransmittersCh 3 4 5 6 on blackboardreviewNeuronsProteinsWhat makes neurons special Proteins filaments enzymesAnatomy Structural proteins filamentsfibersAxons Act pot due to voltagegated channelsMyelinated in vertebratesSynapses Hundreds of presynaptic proteins for transmitters releasepostsynaptic proteins for signallingAbility of cells to relate in fnal wayDNA read to make single stranded mRNA complementary seqchain of aas In ribosome Chemical Synapse single stranded protVoltagegated Na ChannelPostsynaptic membrane is thicked esp in excitatory glutamate recpacked w 100s of prots allowing response to dif signalsgenerate signalsRichest place for prot expressionNeural fns controlled by complicated protsAppears dark on electron microscopeVoltagegated Na channel most important for act Release of vesicle production of transmitters pottransmitters that cause retrogradeHave 6 lipophilic areas going thru membraneAttached in series of loopsProtein Structure
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