HMB200H1 Lecture Notes - Lecture 3: Immunocytochemistry, Antibody

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coppercattle724

18 Jan 2012

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3, 4, 5, 6 on blackboard review. Proteins (filaments, enzymes: anatomy: structural proteins, filaments & fibers, axons: act pot due to voltage-gated channels. Synapses: hundreds of presynaptic proteins for transmitters, release, & postsynaptic proteins for signalling. Ability of cells to relate in f"nal way. Postsynaptic membrane is thicked (esp in excitatory glutamate rec) packed w 100s of prots allowing response to dif signals & generate signals. Release of vesicle, production of transmitters, transmitters that cause retrograde. Protein structure & distribution: dna mrna (spliced) prots (precursors, chopped, can make multiple prots) Chain of dna molec = gene defines prot. Protein chains can be read from dna in genome. Fastest way to find prot is to map genome. Follow codons to read seq of a. a. s determine prot chain. Much more complicated interaction & structure allows for higher f";ns in chemical activity. Primary, secondary, tertiary structure: hydrophilic and lipophilic regions: lipids bind to membranes.

Related Questions

In order to trigger the releaseof neurotransmitter from a neuron terminal, calciumions:

a. exit the synaptic knob through diffusion

b. bind to proteins on the surface of synaptic vesicles

c. penetrate the synaptic vesicles and bind to molecules ofneurotransmitter

d. bind to ion channels on the neuron membrane and cause them toopen for the transmitter

aquamarineseal847

34. Choose the one(s) that is/are an example of homeostatic control (choose ALL that apply):

		Body temperature
		Energy balance
		Increase in atmospheric pressure
		None is correct

32. Which of the following is TRUE regarding chemical synapses? (Select all that apply.)

		They have gap-junctions
		Vesicles fuse with the presynaptic membrane to release neurotransmitters into the synaptic cleft
		When released from postsynaptic membrane receptors, molecules associated with the neurotransmitter may be returned to the presynaptic cell.
		Neurotransmitter is secreted in the synaptic cleft

blacklion206

26. When it comes to ligand-gated ion channels located in a postsynaptic neuron's membrane, why are they so important with respect to how synapses pass along information?

		These channels allow specific neurotransmitters originating in the presynaptic neuron exert effects on the postsynaptic neuron.
		These channels are located specifically in the dendrites but not another part of the neuron, such as the axon.
		These channels open when a given amount of electrical signal in generated in the cell's membrane.
		These channels allow the neurotransmitter to enter and travel within the postsynaptic neuron.

25. When the receptor of a sensory neuron is activated and a nerve impulse is generated, the first step in the overall process would be ____________________________.

		the potassium channels to open
		the hyperpolarization of the membrane
		the repolarization of the membrane
		the depolarization of the membrane

periwinklecoyote319

HMB200H1 Lecture Notes - Lecture 3: Immunocytochemistry, Antibody

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