What is Genetics? How is Genetics relevant to you?
*Genetics: the science of inheritance
•What is inherited?
•How is it inherited?
•Where does heritable variation come from?
•How do heritable traits change over time?
[Why do we care Genetics?--medicine]
-many common and rare diseases/resistances (AIDS, malaria) are inherited
[Ultimate Goals of Medical Genetics]
1) New treatments- identifying disease genes helps in efforts to cure
2) Diagnosis and prediction - Do I have a (presymptomatic) disease, what is the chance my child will?
3) Gene therapy - Replacement of diseased gene with ‘normal’ gene: still experimental
4) Pharmacogenomics - How does my genetic makeup affect my response to drugs?
[Genetics in Business]
Job: genetic prediction = genetic counselling
Company banking human genetics
-screening: how to interpret probability of disease
-privacy (employers, insurance)
-gene therapy (which point is normal? disorder?) [Why do we Care Genetics?—Agriculture]
-crop and livestock improvement (genetic engineering is widespread in Canada)
Ex) more, high quality products, and long term survival against past or other disease
[Why do we car