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Human Biology
Stephen Wright

th LECTURE January 27 Extensions to Mendelian genetics Law of segregation still held but geno-pheno relationship modified Pleitropy, epistasis, etc. effects at one gene or MULTIPLE genes? Independent assortment come into play with dihybrid crosses Monohybrid crossing equal segregation Always recessive always masked Bateson did crosses F1 new phenotype walnut o Weird o Incomplete dominance perhaps???? Cannot self animals but cross F1 male with F1 female o Expect in F2 1:2:1 ratio of walnut, rose, and pea Single phenotype showed up a fourth!! o Cannot be accounted for because Mendel has 3 phenotypes o Cannot break down into one to two to one ratio Saw numbers as nine to three to three to one ratio o Instead of two genes influencing two different traits o Actually two genes influencing ONE phenotype Cf. pleiotropy one gene with multiple phenotypes o Actually recover expected ratios good o W
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