Lecture 17

3 Pages

Human Biology
Course Code
Maria Papaconstantinou

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18 MAR 2011HMB321 L17 Introduction to Model OrganismsWhy use model organismsEasy to growRapidly reproduceSmall sizeLarge collections of mutantsGenespathways conservedGenomes sequenced easier to identify genes with mutant phenotypesPlanarians Flatworm Schmidtea mediterraneaKey organism for studyingDevelopmentStem cell regulationNeuronal behaviourRegeneration Ie Cutting them in half will regenerate a new planarian 2 planariansStudy regeneration in humans as well eg AgingRegeneration is not totally impossible in humans eg Young children regeneration of ngers or hemispheres in the brainFeaturesEasy to groweasy to surgically manipulateaccessible to manipulation Guest Lecture 1 Bret Pearson PlanariansCancerIdentied and characterized the p53 gene in planarians Smedp53 Drosophila Fruit yEggEmbryogenesisLarva eats to grow and developinstar stages imaginal diskspupationeclosionAdultTakes 1011 days depending on temperatureFeaturesG
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