IMM250H1 Lecture Notes - Lecture 9: B-Cell Receptor, Humoral Immunity, Linear Epitope

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14 Apr 2013
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The adaptive immune system is an antigen specific response driven by lymphocytes that respond to antigen, which results in the development of immunological memory. Variable means different types of adaptive immune responses can be generated. The adaptive immune improves over time whereas the innate immune system goes off at the beginning of an infection and stops. White blood cells called b lymphocytes and t lymphocytes make up the adaptive immune system. B lymphocytes will clonally expand after they are triggered by antigen. The clones are all identical to the original antigen-specific b cell and will secrete antibodies. T lymphocytes will clonally expand after they are triggered by antigen. The clones will resemble the initial antigen responsive cell. T cells secrete other molecules such as cytokines and molecules that can directly kill targets. Acquired immunity is the combination of a humoral immune response characterized by the secretion of antibodies and cellular immune response driven by lymphocytes (t cells) and dendritic cells.

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