IMM250H1 Lecture : Notes taken during lecture

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25 Jan 2011
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Innate and adaptive come into play only when these barriers fail. Two organisms capable of entering bodies, bypassing the barrier. Use innate system to defend self against infection. In these lower organisms, innate immunity the only system for protection. versus adaptive system - relatively recent in evolutionary time: unique to vertebrate animals. set number of recognition molecules encoded in genetic material cannot be modified receptors have evolved to detect patterns of microbes that do not change in the huge diversity of microbes. versus adaptive system adaptive immune system infinite number of recognition molecules immediatley active cells versus adaptive system cells need the innate system to prime these cells in order to attack. no memory versus adaptive system, memory of infection see an organism once, see it a second time, body extremely efficient quick to get rid of the infection. The normal response most individuals have to an infection.