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Lecture 3

IMM334 - lecture 3.doc

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Department
Immunology
Course
IMM250H1
Professor
All Professors
Semester
Fall

Description
IMM334Fall 2013Third lecture Mesodermhemangioblastic tissueblood cells Hematopoiesis originate from mesoderm MesodermHemangiogenic precursorHSCmyloid or lymphoid AGM contains cells with HSC function in vivo Fetal hematopoiesis 1 Primitive E75 restricted to yolk sac 2 lineage produces macrophages primitive RBCs transient erythropoiesisno LTHSC2 Definitive Hematopoiesisdefinitive RBC lymphoid precursors LTHSC after E105 in AGM BOTH require SCLTAl1 and Lmo2 transcription factors Both can develop in yolk sac To
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