KPE162H1 Lecture Notes - Lecture 9: Body Fat Percentage, Anaerobic Glycolysis, General Anaesthetic
2 Apr 2019
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Alcohols: hydroxylated hydrocarbons cxhy-oh, beverage alcohol is ethanol (c2h5oh, produced by fermentation (anaerobic glycolysis) of sugars in plant matter by yeast, may be concentrated by distillation or fortified with distilled alcohol, ~ 7 kcal/g when completely burned. In body water-soluble, not very lipid-soluble: distributes into lean body volume. In two people with all factors equal except percentage body fat leaner person will develop a lower blood alcohol concentration (bac) Kpe162: low doses have excitatory effects, inhibits inhibitory neurons in reticular activating system first. Inhibitory neurons in brain stem are most sensitive to drugs: first to get shut down in low doses, higher doses unconsciousness, not sleep (no brain activity) Excretion: first order excretion in exhaled air, not excreted as ethanol by kidney in large amounts traces present in urine, body stores it for fuel, by-products of metabolism (co2 + h2o) are excreted in the usual ways.
