LMP299Y1 Lecture Notes - Lamina Propria, Muscularis Mucosae, Inflammatory Bowel Disease
3 Jun 2013
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Document Summary
Divide into luminal gi liver and pancreas upper tract and lower tract. Upper tract = stomach and small intestine. Liver and pancreas are the two solid organs. Amount of t cells in gut >>> number in spleen most abundant. Mostly t cells with gamma delta receptors mostly cd8 positive. Small intestine surface epitheium villi considered mucosa; then muscularis mucosa; submucosa; muscularis externa; Ileum most prominent lymphoid tissue is peyer"s patch they are lymphoid follicles in lymphoid propria important for gi immunity. Appendix more lymphoid tissue in appendix than lymphoid tissue most common area to find lymphoid tissues/follicles. Closer look at the appendix crypts are glands; Components of the git area between villi lamina propria muscularis mucosae . Lamina propria lymphoid cells are cells in between the villin and intraepithelial lymphocytes are between the epithium in the villi themselves. Fae intraepithelial lymphocytes are fae epithelium on top of lymphoid follicle these are m cells.
