LMP301H1 Lecture Notes - Lecture 1: Hyponatremia, Hyperglycemia, Respiratory Acidosis
14 Sep 2016
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Document Summary
Disease - sickness with characteristic symptoms; response to injury. Biochemical tests use body fluids, are relatively non-invasive, safe, and fast and accurate: define (diagnosis, predict (prognosis, monitoring, find cause (etiology, screening. Prevalence: number of cases of disease in a population. Incidence: number of new cases/unit time in a population. Endemic: most of the population has the disease. Epidemic: widespread o(cid:272)(cid:272)urre(cid:374)(cid:272)e of disease i(cid:374) a populatio(cid:374) where it(cid:859)s rare. Metabolic abnormal production of enzymes/other molecules. Screening for risk of a disease (e. g. heart disease, cancer) Turn-around time, cost, technical expertise, and clinical need are things to consider. Types of markers: physiological (normal range in a healthy person, tightly regulated by body, disease markers (not normally present or only in minute amounts, not regulated by body, normally excreted) Patient self-testing and point-of-care (poc) testing is convenient, but often costly and lacking in qc.
