LMP299Y1 Lecture Notes - Acute Kidney Injury, Renal Function, Renal Physiology

• School: UTSG
• Department: Laboratory Medicine and Pathobiology
• Course: LMP299Y1
• Professor: Kenneth Yip

Document Summary

Objectives: give overview of renal function in waste removal explain causes of acute renal failure explain progression of chronic renal failure discuss treatment in end-stage renal disease (esrd): dialysis and transplantation. Renal function nephron: is the functional unit of kidney: 2 major parts: Filtrate then enters into tubule and water is resorbed and important nutrients as well they are not lost in urine. What is not resorbed goes down the urethra and into bladder and is then excreted. The amount of blood flowing thru kidney is very large: measure of gfr: measures the amount of creatinine that passes thru kidney in. If one removes, say, 1440 mg in 24 hours, this is equivalent to removing. They are pharmacologically inert substances that are given intravenously. They increase theosmolarity of blood and renal filtrate: osmotic diuretics works by expanding extracellular fluid and plasma volume, therefore increasing blood flow to the kidney. This washes out the cortical medullary gradient in the kidney.