MGY277H1 Lecture Notes - Lecture 4: Prenatal Development, Cestoda, Signify
2 Apr 2017
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Document Summary
Fungal pathogens are particularly problematic for people who are. Immunocompromised individuals who have weak immune system due to aids, immune-suppressive drugs, or other infections. Opportunistic only ccasue disease in immunocompromised individuals. Primary can also cause disease in otherwise healthy individuals. All eukaryotic organisms fall into domain [eucarya] range from plants to animals to microscopic members (animals , plants, fungi, protista) Cell wall contains chitin (same molecule that forms the exoskeleton of insects) vs. bacteira cell wall made of peptidoglycan. Cell membrane composed of ergosterol vs. animal cell membrane compsoed of cholesterol (ergosterol biosynthesis is a major anti-fungal drug target) Different species of fungi can exist in multiple forms: single celles-yeast, multi-celled filaments (hyphae or pseudohyphae, spores. Fungal spores everywhere on earth, up to altitudes of more than 7 miles (air may contain >10,000cells/m3) With each breath you take, it is estimated that you breath in 5 fungal spores.
