MGY277H1 Lecture Notes - Lecture 10: Humoral Immunity, Thymus, Epitope
2 Apr 2017
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Document Summary
Microbes are tolerate or even encourages to grow at some sites. Those exact same microbes can be deadly if introduced to a different site in the body that is meant to be kept sterile. Examples: if e. coli in the colon goes into the blood stream you will duffer from sepsis (life threatening condition) Multiple distinct mechanisms work together to control microbial growth in our tissues. No single system is sufficient to protect us from all microbes. Some boarder are though to be inside the body but they are in contact with external environment. Digestive tract starts at mouth, ends at anus. Constantly bathed in secretion (mucous) wash microbes away. Peristalsis of intestines, mucoiliary escalator of respiratory tract move microbes to areas for eliminateon (i. e when you blink/pee, etc) But they are frequency location of infection. Intestine bacteria are resist to it modify to create secondary bile acid more portent and prevent competing microbe from establishing home.
