MGY377H1 Lecture Notes - Lecture 12: Endopeptidase, Aureus, Lysozyme
1 Feb 2018
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Denepding on the endopeptidase, it can cut these bonds. These enzymes are proteases that cut these (cid:271)o(cid:374)ds, (cid:271)ut the(cid:455) (cid:449)ould(cid:374)"t ta(cid:396)get p(cid:396)otei(cid:374)s (cid:373)ade f(cid:396)o(cid:373) (cid:396)i(cid:271)oso(cid:373)es, the(cid:455) spe(cid:272)ifi(cid:272)all(cid:455) ta(cid:396)get (cid:272)ell (cid:449)all structures. Glucosaminidases cut in the center, if they cut at the terminal bonds re called neuramidases. This is the first enzyme to ever have its structure solved. This was proced in the arms rwace between 2 staphlococcus species. This enzyme can pop straph aureus cells, its specific to staph aureus. The peptidoglycan determines the cell shape, it makes the cell wall. If (cid:449)e (cid:396)e(cid:373)o(cid:448)e the ge(cid:374)e, the (cid:271)a(cid:272)te(cid:396)ia (cid:449)ill die. The (cid:395)uestio(cid:374) is ho(cid:449) do (cid:449)e (cid:449)o(cid:396)k o(cid:374) a ge(cid:374)e that"s essst(cid:374)tial genetically. When the temperature was increased, the ecoli cells turned into these spaghetti like fillaments, and they were called the fts mutants. Maybe the genes that were lost were the genes that cut the cell in hald during growth.
