Class Notes for Molecular Genetics and Microbiology at University of Toronto St. George

find more resources at oneclass.com MGY277 Lecture 01 UNIT 1 - The germ-theory of disease Edward Jenner o Berkeley England o Developed the used of cowpox to vaccinate against smallpox (Va...

Lecture 9: Immunity and Vaccines Healthy Microbes Most of our internal organs are virtually sterile (e.g. bones, stomach, bladder, blood) More exposed regions are not sterile (i.e. mouth, skin) Microbes are...

Lecture8:Epidemiology Epidemiology Epidemiology is study of disease patterns in populations Epidemiologists (health detectives): o Collect, compile data about sources of disease and risk factors ...

Lecture 7: Antimicrobials and Antimicrobial Resistance Importance of Antimicrobials Before antimicrobials prognosis for people with common diseases was grim (i.e. before penicillin in 1940s) World war II w...

Lecture11:IntroductiontotheHumanMicrobiota The Human Microbiota Microorganisms play a vital role in human health For example, brush your teeth and floss to prevent dental plaque (microbial biofilm cavities) ...

Lecture 10: Principles of Pathogenesis Principles of Infectious Disease Colonization: refers to microbe establishing itself on body surface or mucosal layer Infection refer to colonization by a pathogen ...

Lecture 6: Microbial Identification and Classification Questions: 1. Describe how prokaryotes are identified, classified, and assigned names. 2. Describe how phenotypic characteristicsincluding microscopic 3...

Lecture5:ControllingMicrobialGrowth Traditional Culturing Methods Conditions are usually optimized for rapid growth o Most studies on bacteria have been carried out on bacteria in this state. Bacteria ...

Lecture 4: Eukaryotic Microbes Questions: 1. Know the difference between an opportunistic and primary pathogen. 2. Know what differentiates a eukaryotic cell from a prokaryotic cell. 3. Be able to list the de...

Lecture3:Viruses Questions: 1. Describe the physical and genomic features of viruses. 2. Understand how viruses are classified and grouped. 3. Describe the 5-step infection cycle for enveloped and non-envelop...

Lecture2:Bacteria Questions 1. Define the terms magnification, resolution, contrast, and refraction and apply them when looking at an image from a micros klcope 2. Recite the steps of a Gram stain and why ...

Lecture 1 Questions: 1. Describe the impact infectious disease (and the control of infectious disease) has had on our population. 2. Recall the main players in the Germ theory of disease and their associated discoveries 3....

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Unit 1: Perspectives on Medical Genetics Introduction to Medical Genetics Chronic Myeloid Leukemia (CML) - Cancer transformed by treatment - Chemotherapy is only 30% effective - Gleevcc -> survival af...

Unit2 The Bacteria Magnification: increase in apparent size of object (e.g. 4x appears 4 times larger) Refraction: when light rays change direction due to change in medium, only bends at interface between mediums o Refract...