NFS284H1 Lecture Notes - Lecture 13: Cretinism, Collagen, Insulin Receptor
Document Summary
Iron is the most common micronutrient deficiency in the world. Non- heme iron: plant sources (leafy greens, legumes, grains). Using iron cookware with acidic foods is a way to increase iron consumption without increasing calories: essential component of the heme group, which sits inside the proteins hemoglobin or myoglobin. Non heme iron is usually found in ferric form (fe+++) and is converted into the ferrous form (fe++), which is absorbable. Iron supplements contain ascorbic acid (vit c), which helps to keep the iron in the more absorbable ferrous form. Protein from animal sources also enhances the absorption of nonheme iron. Iron enters the enterocyte (whether non-heme or heme: ferric iron then gets converted to ferrous form, binds to a copper containing protein, enters circulation, gets picked up by a transport protein (transferrin) It can be stored in the liver, it"ll go to the bone marrow. There"s no way in excreting iron, so the body is good at recycling it.