NFS284H1 Lecture Notes - Vitamin B12 Deficiency, Thiamine, Megaloblastic Anemia

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18 Dec 2013
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Must be listed in the nutrition facts table. Mouth chewing releases the vitamins from food. Stomach digestion releases the vitamins from food some niacin absorption. Gall bladder bile absorbs fat-soluble vitamins. Pancreas digestive enzymes releases the vitamins from food. Fat-soluble vitamins (micelles) brush border mucosal cells (chylomicrons) lymph blood: water-soluble vitamins blood. Large intestine bacteria synthesize small amounts of vitamins. Bioavailability how much a nutrient can be absorbed and used in the body. Water-soluble vitamins: no storage, excess excreted in urine, depleted more quickly than fat-soluble vitamins, vitamin b12 stays in the body for several years (exception) Stored in the liver and the adipose tissue. Molecule + active enzyme = enzyme reaction. Enzyme reaction = to form one or more new molecules. Energy metabolism: thiamin, riboflavin, niacin, pantothenic acid, biotin. Single carbon metabolism transfer of methyl groups: vitamin b6, vitamin b12, folate. Antioxidants protection from oxidative damage or oxidative stress: vitamin c, vitamin e.

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