PCL102H1 Lecture Notes - Lecture 23: Toxicology Testing, Health Canada, Antigen

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So(cid:373)eti(cid:373)es (cid:271)iologi(cid:272)s (cid:272)a(cid:374) result with i(cid:373)(cid:373)u(cid:374)e rea(cid:272)tio(cid:374) (cid:271)e(cid:272)ause they are su(cid:272)h large (cid:373)ole(cid:272)ules, the (cid:271)ody s immune system can react to it. To prevent this, there needs to be toxicology testing and it needs to start with small doses and slowly escalate the doses. Biologics have advantages at the beginning of the processs, but at the end of the processs the advantages are lost. Health canada has no role in drug pricing, it only makes sure the drugs are safe.

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