PCL102H1 Lecture Notes - Amita Sehgal, Prodrug, Oxcarbazepine
Document Summary
1 introduction: most people with seizures are normal between attacks, and seizures themselves are usually brief and relatively harmless. The answer is that seizures have an impact on human life that is far out of proportion to their medical significance: seizures look strange, even frightening, and the public reacts badly to them. People with uncontrolled seizures may face the loss of friends, jobs, and housing: in addition, people with uncontrolled seizures are not permitted to drive motor vehicles. Query: should drug therapy be offered first: firstly, don"t treat the first seizure unless the eeg shows brain abnormalities, dr. burnham thinks he would opt for potential surgery before trying drugs. Query: how about the co-morbidities: memory problems, depression, anxiety. 2 terminology: a large number of drugs suppress seizures (e. g. , most hypnotics. [sleeping pills], sedatives [generally anxiolytics], and anesthetics): all the downers stop seizures.