Class Notes (835,600)
Canada (509,275)
Pharmacology (260)
PCL201H1 (59)
Worlsey (24)
Lecture

Lecture 25 Adverse Drug Reactions

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Department
Pharmacology
Course
PCL201H1
Professor
Worlsey
Semester
Winter

Description
Lecture 25 Adverse Drug ReactionsTeratogenesisDrug use in pregnancyDrug effects in pregnancy rarely evaluated befre market releaseUse not recommended unless benefits justify riskTeratogenic factor with harmful effect n fetusTypes of malformationsMajor structuralfunctional defects medicalsurgical intervention necessary incompatible with life impair individuals capability to function normally in societyMinor unusual morphological traits no serious medicalcosmetic consequences to childThalidomideAntiemetic during pregnancyLimb reduction defect other abnormalitiesCritical period of exposure 4550 days after first day of last menstrual periodCritical PeriodsPregnancy 3 trimesters 3 months eachAlso can be divided into eggembryof
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