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Lecture 3

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Department
Physiology
Course
PSL201Y1
Professor
Michelle French
Semester
Fall

Description
PHSIOLOGY LECTURE 3 Sept 24, 2013 Dr. Kee Phase I: membrane becoming more positive as more sodium coming inside cell through voltage-gated channels As membrane becomes more depolarized, more voltage gated channels open, again allowing more sodium again. A cycle. Sodium comes inside cell very quickly. Equilibrium potential for sodium is: +60mV that's what sodium wants the membrane to be But MP never reaches +60 because there's other ions involved (K) Phase II: Repolorization But about half a millisecond after sodium volatge gated channels open, they start closing. for that reason, MP never reaches +60mV channel is inactivated when membrane reaches +30mV basically a fight btw what K wants and what Na wants after sodium channels close, K still has its leaky channels open. K goes in. Therefore, making membrane more negative. K has leaky channels and voltage gated chan
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