PSL201Y1 Lecture Notes - Lecture 4: Hydroxylapatite, Parathyroid Gland, Rank
Document Summary
Wave of calcium signalling changes membrane properties so no other sperm can enter. Total body ca2+= intracellular + extracellular (ecf/plasma + bone: ca mainly in hydroxypatite crystals, small fract"n readily ionized & exchangeable (fluid around this area, good since has get ca from here if not enough in blood. ~16: have to maintain approx 25mmol ca2+ in, ~20mmol taken in per day, excrete in feces, only absorb ~4, by small intestine, can remain in extracellular fluid or go into bone. 99% stored in minerals of bone: ca2+ filtered into kidneys, filtrate modified collects into bladder; >4mmol ca2+ filtered but some reabsorbed; 4mmol lost in urine balanced by ca2+ brought in thru diet. If have too much ca2+ lose thru urine thru for signalling: 0. 001mm in cell, allows effect when rushes. Bone is constantly being formed & resorbed, dynamic. Formed from immune-like monocyte: monocytes fuse together, produce lysosomes.
