PSL201Y1 Lecture Notes - Osmotic Concentration, Membrane Transport Protein, Osmosis
Document Summary
A 37 year old woman completed her fourth marathon in 4hrs and 35mins. + she was taken to the emergency room 6hrs later because she was suffering from mental confusion. + her initial serum [na+] was 121 mmol/l. The total body water has 42l of volume 60% of body weight. Exclusion (no water): lumen of the gut, tubules of the nephron, air part of the lungs. + water inside the cell, in the tissues. + water found in blood vessels and cell membrane. + the fluid outside of the cells tissues and the blood. + fluid that surrounds cells inside in the tissues. Interstitial fluid and plasma are divisions of the extracellular fluid. Water distributed in these different compartments through osmosis. Hydrophobic (and water) cross the phospholibid bilayer. + water molecules are small so they"re able to get through the layer, but not too fast. Hydrophilic (ie: ions, glucose, amino acids, water) use membrane transport proteins for transport.
