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Lecture 6

PSL 300 Lecture 6

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Department
Physiology
Course
PSL300H1
Professor
Gillian Mac Kay
Semester
Fall

Description
PSL300 LECTURE 6 BLOODBRAIN BARRIERBlood Brain Barrier3 distinct barriers 1Blood interstitial fluid2Cerebrospinal Fluid ventricles3CSFinterstitial fluid Free diffusion between CSF and CSF interstitial fluidNa of bloodNa of interstitial fluid K of bloodK of interstitial fluid since too much K could lead to depolarization block Protein of bloodprotein of IFBrain EncasingsSkullDura MaterArachnoidSubarachnoid spacefilled with CSF to make a suspension cushion ie brain floats otherwise brain would impact with skullPia Matertethered to arachnoid by arachnoid trabeculaeThere are filaments teetering the arachnoid to pia materAstrocytesGlial cells that wrap around synapsesDoes a lot of metabolic work eg mopping up neurotransmitterTakes gl
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