PSL301H1 Lecture : Lec 1
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PSL301H1 Full Course Notes
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Primary function of the lungs (cid:131) remember: function determines structure, and structure determines function (cid:131) the primary function of the lungs is to exchange gases between blood and air. 5% in blood (cid:131) gas exchange occurs by passive diffusion across the alveolar membrane separating air and blood. No gas exchange occurs and so they make an anatomical dead space (more later on that). The alveolar wall (cid:131) for gas exchange, the pulmonary capillaries form an almost continuous sheet covering the walls of the alveoli: minimize thickness of the alveolar membrane to maximize gas transfer. Pulmonary defence systems (cid:131) because of its large surface area of delicate tissues, the lungs must be defended against air pollution: once damaged, lung tissue rarely recovers (smokers never regain lost lung function). In the alveoli, particles are engulfed by macrophages. (cid:131) many occurring exocytosis prevents gas exchange and causes lung problems. = inspiratory reserve volume + expiratory reserve volume + tidal volume.