PSL350H1 Lecture Notes - Lecture 2: Eye Color, Central Dogma Of Molecular Biology, Dna Replication

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19 Jan 2018
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Gertrude and charles davenport (husband and wife duo) 1907 studied eye colour of 77 families for 3 generations. One gene for eye colour because 2 blue-eyed parents will have only blue- eyed children: blue is recessive to grey which is recessive to brown. As propo(cid:374)e(cid:374)ts for the (cid:862)o(cid:374)e ge(cid:374)e(cid:863) side of the de(cid:271)ate, the(cid:455) ig(cid:374)ored data that (cid:449)as inconsistent with their theory: 2 blue-eyed parents had a grey eyed child, (cid:272)alled it (cid:862)slight i(cid:374)a(cid:272)(cid:272)ura(cid:272)(cid:455) of (cid:272)lassifi(cid:272)atio(cid:374)(cid:863) The central dogma describes the flow of genetic information in all living cells. There are variations of these processed among different types of organisms. For e(cid:454): rna pro(cid:272)essi(cid:374)g (cid:894)5" (cid:272)appi(cid:374)g, i(cid:374)tro(cid:374) sli(cid:272)i(cid:374)g, etc. ) only occur in eukaryotic cells, not bacteria. Quote: short term survival of a cell can require it to avoid changes in its dna, but the long-term survival of a species requires it to have changeable dna to permit adaptation. Every time dna replicates, about 1 in 10^10 nucleotides will mutate/change.

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