PSL300H1 Lecture Notes - Lecture 6: Receptor Tyrosine Kinase, Glucagon Receptor, Insulin Receptor
Document Summary
A 28-year-old woman with extreme thirst and frequent urination (symptoms started 3 months ago). Drinks 1 15 large classes of water and several cans of soda over 2-3 hours. Appears normal, 5 ft tall, 128 lbs, blood pressure 102/68, pulse 72. Dysregulation of avp (can either be increase release of avp, or hyperactivity of the receptors. Urine analysis to determine osmolarity (if low, you know it"s not because of increase in glucose) She probably has diabetes insipidus which is a rare genetic defect. Sum of all chemical reactions in the body. Energy types: carbohydrate: 4 kcal/g, protein: 4kcal/g, fat: 9 kcal/g. Biggest reservoir of calories: carbohydrates and protein are used most often; they have the same energy per gram. Energy expenditure: 50% of energy is spent on thermoregulation. 37oc/unregulated heat loss: 50% spent on cellular activities. Basal metabolic rate (bmr) = an individual"s energy expenditure when resting, comfortable temperature, fasted: distinct from bmi, specific for you.
