PSL301H1 Lecture Notes - Lecture 12: Bicarbonate Buffer System, Sodium Bicarbonate, Proximal Tubule
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PSL301H1 Full Course Notes
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When you and i eat a normal diet, contains sodium, water, potassium; but dominated by foods that generate acid as well, making h ions, that our kidney must play a role in eliminating it. Case of the day someone who wouldn"t wake up (cid:523)common in the winter? (cid:524) Ph was profoundly more acidic than normal. Pco2 at a normal value; we breathe in oxygen, exhale and it excretes co2. Lower hco3, somehow has added acid and titrated his hco3 concentration down. Kidney maintains h+ ion balance in the body. What is the ph in different body fluids? secretion of acid in stomach causes ph=1. 5. H ions comes from metabolism fat is not considered a source of h+, as well as sugar ph balance in the body. No net acid addition in normal physiology, but pathophysiology may come from lactic acids/ketoacids. Bicarbonate is what we inherently have that is the first line of defense against.
