PSL301H1 Lecture Notes - Lecture 36: Lactose Intolerance, Exopeptidase, Glut5
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Document Summary
Glucose polymers like starch and glycogen can be digested into disaccharides, then further digestion occurs into monosaccharides for absorption. Mouth: 5% of starch is broken down into maltose by salivary amylase the longer you keep the bolus of food inside our mouth with salivary amylase, the more breakdown of carbohydrates. Stomach: digestion continues until amylase exposed to low ph salivary amylase becomes inactivated when in a low ph environment 35% of starch is broken down. Small intestine: pancreatic amylase more potent than salivary amylase continue digestion of carbohydrates, similar catalytic property with salivary amylase. Enzyme have optimal ph for where they work best. Sglt1 symporter transport glucose/galactose along with na+, and sugar is moved down the concentration gradient and out of the cell into the capillary via glut2 transporter. Fructose moved into the cell via glut-5, and move into the capillary via the same. Glucose levels are high in the enterocyte (cells of intestine lining)