PSL301H1 Lecture Notes - Lecture 18: Peripheral Chemoreceptors, Aortic Body, Hypocapnia

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13 May 2020
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PSL301H1 Full Course Notes
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** no questions on exercise; was not covered in class ** The freediver hyperventilates, which causes co2 levels to decrease. This is because high co2 levels triggers breathing. As the diver stays underwater, the o2 levels decrease. Eventually, the o2 levels drops below the o2 blackout zone; the diver passes out. Co2 is the most important stimulus for changes in ventilation; o2 and plasma ph are less important. If someone gives you co2 respiratory rate increases to eliminate this co2. Linear relationship between co2 given and ventilation. Located in the medulla and some other brain tissues. They monitor h+ in the csf and arterial circulation. The chemoreceptor is activated by h+; however, this crosses to the csf as co2. What we know if from animal studies, can"t image the brainstem due to the skull. Located in the carotid and aortic bodies. Monitors arterial levels of o2 and co2/h+ The respiratory system is also controlled by arousal.

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