PSL301H1 Lecture Notes - Lecture 19: Obstructive Sleep Apnea, Phrenic Nerve, Peripheral Chemoreceptors

24 views2 pages
13 May 2020
School
Department
Course
Professor
elliehaj0807 and 36989 others unlocked
PSL301H1 Full Course Notes
41
PSL301H1 Full Course Notes
Verified Note
41 documents

Document Summary

French physiologist first scientists to understand the role of the brain in breathing. Saw the mouth of the convict opening rhythmically before, we thought breathing was done by the lungs but he said it was done by the brain. Diaphragm muscle innervated by the phrenic nerve (two that innervate each side) Upper airway muscles innervated by the hypoglossal nerve (cn12) Abdominal muscles innervated by thoracic spinal nerves. Medullary respiratory centres located in the medulla and pons. Dorsal respiratory group (drg) receives input from the lungs, peripheral chemoreceptors and different parts of the cardiovascular system. Ventral respiratory group (vrg) centres that generate rhythmic breathing; also has expiratory activity; synchronizes inspiration with expiration. Neurokinin-1 receptors activated by substance p. Upper airways relax when we sleep, leading to a collapse of the airway; the diaphragm works but there is no air flow. Symptoms: daytime sleepiness, depression, hyperactive behaviours, repeated desaturation during the night. Long term consequences: cardiovascular disease (hypertension) and stroke.

Get access

Grade+20% off
$8 USD/m$10 USD/m
Billed $96 USD annually
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
40 Verified Answers
Class+
$8 USD/m
Billed $96 USD annually
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
30 Verified Answers

Related Documents