PSL301H1 Lecture Notes - Lecture 2: Opsonin, Interferon, Thymus

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17 May 2016
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PSL301H1 Full Course Notes
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Main features of immune system are specificity and memory: allow body to distinguish between self from non-self during immune response, 3 major functions. Cancer cells form regularly but are usually detected and destroyed by immune system before they get out of control. Scavengers cells such as macrophages patrol extracellular compartments. Almost any foreign molecule can induce an immune response: known as immunogens, immunogens that react with antibodies are antigens. Viruses can replicate only inside host cells: virus binds to membrane receptors of cell, triggering endocytosis of virus. Free of capsid shell, virus rna/dna hijacks the cell"s transcription and translation machinery to make new viral nucleic acid and proteins. Virus causes host to lyse and release viral particles into ecf. Virus particles embed themselves into a vesicle then bud off. Psl301h1|lecture 2: detection and identification of foreign substances, communication with other immune cells to organize response, recruitment and coordination of response among cells, destruction of invader.

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