PSY100H1 Lecture 6: Lecture 6

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PSY100H1 Full Course Notes
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PSY100H1 Full Course Notes
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Manipulating action potentials: alter the amount of neurotransmitter release. Amphetamines cause massive dumping of catecholamines, (e. g. dopamine) increasing the amount of neurotransmitter released. 2) block the removal of the neurotransmitter from the synapse (ssris) (cocaine blocks reuptake of dopamine in nucleus accumbens) 3) make the post-synaptic receptors more or less sensitive (e. g. nicotine enhances sensitivity of the post-synaptic receptor for dopamine) desensitization occurs. Remember, the synaptic cleft connects the terminal buttons of one neuron, to the dendrites of another. most prevalent excitatory neurotransmitter in the cns (learning and memory) most prevalent inhibitory neurotransmitter in the cns (inhibition of seizures, anxiety disorders) if you reduce gaba activity, you will enhance. cns functions: complex mental processes (memory), alzheimer"s patients have low levels of ach. depression (not enough n), anxiety (too much n) mood (and therefore depression, anxiety, various emotion and motivation problems) universal pleasure mechanism and the common bond among drugs of abuse)