PSY372H1 Lecture Notes - Lecture 7: Protein Synthesis Inhibitor, Propranolol, Lisa Kudrow
Document Summary
Psy372 - lecture 7: future directions in memory research. Consolidation/reconsolidation: background information: learning induces changes in synaptic efficacy. Long-term potentiation (ltp): which is increased synaptic efficacy in response to an experience, and the ease at which. Some aspects of ltp require protein synthesis: disruption of protein synthesis (e. g. using the protein synthesis inhibitor anisomycin) you will disrupt memory formation. Short-term memories consolidate into long-term memories and become stable to change (a) Stms are transient memories that do not require protein synthesis (therefore can be expressed immediately) Ltms are stable memories that develop over time. Mediated by changes at synapse and require protein synthesis. Consistent with this view, disrupting protein synthesis (using protein synthesis inhibitor anisomycin) immediately after learning impairs long-term memory but not short-term memory (b) What happens if the memory is reactivated? (e. g. exposure to the training environment or the conditioned stimulus)