The tissues are disorganized and poorly differentiated, so they"re essentially becoming more primitive. Oh ye, they can, but they won"t necessarily become malignant. Which is why early screening is so important you nerds. They mess with the regulation of genes responsible for growth, apoptosis, etc One of these jerks that cause insertional mutagenesis. Nah, there"s a human equivalent that"s known as the proton-oncogene. The virus picks up a gene important for cellular growth, but not the correct regulation, so it"s constantly expressed, doesn"t fall under regular growth restrictions, which then causes the host to produce the cell and it just. keeps. growing. It can disrupt regulation, which would then lead to the constant production of something (verbatim from my notes. They interfere with immune function: tissue destruction, chronic inflammation, leading to constant cell proliferation, enhancing mutation rates. Hbv, hcv, and people with these diseases are more likely to develop cancer. They can directly stimulate the proliferation of cells.