BIOL 329 Lecture Notes - Lecture 46: Soricomorpha, Carnivora, Even-Toed Ungulate

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Lect 46
Gene drive for control of exotics. Gene drives = genetic constructions that can be inserted into DNA to
change the rules of inheritance in sexual reproduction. They can boost the chances that a particular trait
will pass from a parent offspring from 50-50 to nearly 100%.
The technology so far is limited in the lab but many scientists hope to eventually use it to control
disease-carrying insects, invasive species and other problematic organisms. Drives the gene to fixation.
Could be a gene drive for sex, etc. Only a small number of individuals are needed to drive the gene to
fixation.
Use CRISPR nuclease Cas9 to serve as a general method for spreading altered traits through wild
populations over many generations. Works well for insects. Not well for birds because they return to
their original habitat; altered traits could spread through entire species and wipe it out.
Will not be tested on gene drive
Exam question: walk through Mystic Vale would give insight to this. Genetically similar species in the
same habitat. Paper on coloration of European songbirds irrelevant. Evaluated it without context of
the habitat where birds live in.
REVIEW
Raptors: biomagnification, native vs invasive species.
Cetaceans (guest lecture): aspects of sound production what was being characterized. Relative
abundance of cetaceans, how many species.
Caribou lecture: no questions from guest lecture but general info.
Relative order of abundance of mammals: rodents, chiroptera, soricomorpha, primates, carnivora,
artiodactyla. Keep in mind: mammals of BC
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Document Summary

Gene drives = genetic constructions that can be inserted into dna to change the rules of inheritance in sexual reproduction. They can boost the chances that a particular trait will pass from a parent offspring from 50-50 to nearly 100%. The technology so far is limited in the lab but many scientists hope to eventually use it to control disease-carrying insects, invasive species and other problematic organisms. Could be a gene drive for sex, etc. Only a small number of individuals are needed to drive the gene to fixation. Use crispr nuclease cas9 to serve as a general method for spreading altered traits through wild populations over many generations. Not well for birds because they return to their original habitat; altered traits could spread through entire species and wipe it out. Exam question: walk through mystic vale would give insight to this. Paper on coloration of european songbirds irrelevant. Evaluated it without context of the habitat where birds live in.

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