PSYC 251 Lecture Notes - Lecture 2: Axon Hillock, Threshold Potential, Resting Potential

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purplesardine872

22 Jun 2018

School

University of Victoria

Department

Psychology

Course

PSYC 251

Professor

Adam Krawitz

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 Hodkin-Huxley Model

o Mathematical Model of Action Potentials

 Propagation of Action Potential

 Active

 Slow, Self-regenerating, travel long distance

o Saltatory Conduction

 Nodes of Ranvier (action potentials)

 Myelinated Sections (electronic conduction)

 Fast, Self-regenerating, travel long distances

o Speed

 Slowest (<1 m/s)

 Fastest (>120 m/s)

 Depends on…

 Axon diameter, myelination, temperature, etc…

 Synaptic Transmission

 Passing signal form one cell to next

 Presynaptic action potential -> postsynaptic potential

 Postsynaptic Potential

 Neurotransmitters (form presynaptic cell)

 Over 100 discovered!

 Ions, amino acids, proteins

 Localized within presynaptic neurons

 Stored in terminals

 CNS

 GABA

 Acetylcholine

 Dopamine

 Serotonin

 Noradrenaline (nonipiphrine)

 Histamine

 Biochemical Classifications

 Amino Acids

 Monoamines

 Peptides

 Gases

 Other

 Receptors (Postsynaptic Cell)

 Ionotropic

 Ligand-Gated Ion Channel

 Acetylcholine Receptor Channel

 Metabotropic

 Second Messenger Cascade

 G-protein Coupled Receptor

 Excitatory (EPSP) / Inhibitory (IPSP)

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PSYC 251 Lecture Notes - Lecture 2: Axon Hillock, Threshold Potential, Resting Potential

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